"I don't think they wanted anything from me. They liked me. As I liked them," Duduzane told the BBC, sitting in a Dubai hotel room.
"There's nothing untoward about it... It was just a meeting of minds -- they understood me, I understood them."
- A chink in Zuma's armour? -
President Zuma, who has at least 20 children and has been married six times, is due to stand down in 2019.
But he has been engulfed in corruption scandals that have fuelled growing calls from within the ruling ANC party for him to resign.
Among the many allegations, he is accused of unfairly granting lucrative government contracts to the Guptas and even taking their orders over ministerial appointments.
EFF lawmakers are not the only critics of the president who see Duduzane as a chink in Zuma's armour.
OUTA, a civil action group, last month laid fraud charges against Duduzane and the three Gupta brothers -- Atul, Ajay and Rajesh.
"Duduzane provides access to his father (and) amassed a vast fortune," OUTA alleged.